Not that I've noticed.
Also got AMD-NR to work in VR. I installed the NR through zmodelerlover's installer on GitHub then did what was described below but renamed to d3d11.dll instead of dxgi.dll
Had some BepinEx mods that seemed to cause problems with SteamVR so removed them all, but I still...
It's easy if you install reshade with add-on support (DX11) to the folder manually then use AMD-NR ReShade Installer by zmodelerlover on GitHub to do the rest. It won't work in VR for VAM specifically though. Not that you'd want to use AMD-NR in VR since the performance is unusable if my testing...